New Pill Approved By The FDA Alerts When A Dose Is Missed

Today the FDA announced a new drug approval for Abilify MyCite, complete with a sensor that can digitally track whether or not a patient has taken their medication. The pill includes a sensor that can be ingested and can alert doctors if a patient taken or missed their dose.

FDA Approves New Drug to Track Patient Dosing

Abilify is most commonly taken for patients diagnosed with schizophrenia and bipolar I disorder. The patient must wear a patch that can transmit data via a mobile application on their smart phone or can give permission to share the updates with a designated family member or doctor. Individuals with permission to access the information can also do so in an online portal.

“Being able to track ingestion of medications prescribed for mental illness may be useful for some patients,” said Mitchell Mathis, M.D., director of the Division of Psychiatry Products in the FDA’s Center for Drug Evaluation and Research. “The FDA supports the development and use of new technology in prescription drugs and is committed to working with companies to understand how technology might benefit patients and prescribers.”

It’s a known problem that patients taking medications for a wide variety of reasons stop taking their doses when they start to feel better without realizing the reason for their overall improvement is due to their regular adherence to taking proper doses. While there is no correlation yet between the new tracking capability for Abilify and a patient’s willingness to share the information with prescribers, hopefully in the future, hopefully this will help keep patients on track.

Read the full press release from the FDA Here.

ChemicalInfo Wins DFW Torch Award

ChemicalInfo was the proud award recipient of the 2017 DFW Award for Ethics. The Torch Awards sponsored by the Better Business Bureau Serving North Central Texas and Dallas Business Journal evaluated organizations based on integrity and ethics in business dealings, education, business-to-business recommendations, customer service and other criteria.

As the winner in the small category, ChemicalInfo shared its drive for all employees to adopt its core values, Ownership, Trust, Commitment and Fun every day and to nominate their peers to that exemplify these values. At the end of the quarter the employee with the most nominations becomes the Employee of the Quarter and receives recognition and monetary compensation.

Read the full published article below or click here.

ChemicalInfo wins DFW Torch Award for Ethics. Photo Credit BBB Serving North Central Texas

Chemicals America 2017 Show Wrap-up

The 2017 Specialty Chemical and Agro Chemicals America show was a great success! Once again our company provided exhibitors and attendees with free access to SourceFinder to provide visitors with an efficient way to research and plan their trip. Registrants can search by product, CAS #, or company name and view company information including full product catalogs, contact information, certification information, and contract/custom manufacturing details. Access is still available so register today for sourcing information and contact details.

Also at the show, we were pleased to be a part of the Mixer Direct 8 Companies You Should Know From the 2017 Specialty Chemical and Agro Show video series. Watch the video below.

Chemical Info

I’ll Drink To That: New Study Proves Why Adding Water to Whisky Enhances the Flavor

A recent study conducted by two Swedish chemists proves that adding a bit of water to whisky does in fact improve the overall taste. I know that adding water to whisky is common but I always thought it was the equivalent of asking for ketchup at a nice steakhouse. I have a great uncle who did that and it’s still a running joke in my family… tip don’t do that in a steakhouse. The team conducted a series of tests to determine how and why adding water contributes to the taste enhancement by specifically focusing on the presence of guaiacol, an organic compound found in drinks like whisky and coffee.

Guaiacol is used in the creation of flavors such as vanilla and can be found when wood is smoked or burned, such as the charred barrels that global distilleries use to create their finished whisky products. This study centered on the presence of ethanol (main ingredient of whisky) and what happens when it is diluted from its common 70% alcohol by volume to its standard 45% alcohol by volume state. Yes, whisky already had water added to it when you buy it, so why would anyone want to add more?

The team discovered that adding a bit of water (starting with a few drops) causes the ethanol content of the drink to rise to the surface because it has a higher density. Guaiacol isn’t a fan of water and tries to stick closely to ethanol which is now concentrated on top of the drink. Adding water actually makes the taste more potent and enriches the aroma of the drink and if you’re a foodie like me, you know that smell has a lot to do with taste.

The study also warns whisky connoisseurs not to overdo it because, “There is a fine balance between diluting the whisky to taste and diluting the whisky to waste.”

So there you have it, adding an ice cube or a splash of water to your whisky will enhance the flavor, so bottoms up and cheers!

You can read the full study published here.

Just for fun, check out The Chemistry of Whisky infographic published on

Chemistry of Whisky Infographic

New 2016 U.S. Port Report Available Now from Descartes’ Datamyne

Datamyne U.S. Port Report

At ChemicalInfo it is our mission to connect buyers and sellers of chemicals and pharmaceuticals with the most accurate sourcing and procurement data available. Earlier this year, we announced the integration of U.S. waterborne import-export information based on ship manifests and bills of lading from our partner, Descartes’ Datamyne.   A leading provider of global market intelligence, Descartes Datamyne has released its 2016 U.S. Port Report covering the top 20 ocean ports in the United States. This report includes detailed information about top importers, countries of origin for incoming shipments, and a breakdown by top HS products (ranked by value) at each individual port.

If your business is not using trade data to monitor competitor activity, qualify buyers and find new suppliers, then it’s probably missing out on new ways to find global business opportunities.

Download the complimentary report now and see for yourself how trade data can provide your business with valuable insights.

Would you give up yoga pants to save the sea?

In a recent article published by Chem.Info it shared that a recent study conducted by a team from the Mississippi-Alabama Sea Grant Consortium has seen that tiny microfibers have been flowing down bathroom sinks and shower drains and into our oceans. Comfy articles of clothing made from fleece, nylon and polyester contain these tiny microfibers and each time those pieces of clothing are washed, once the water drains it is carried through our water systems and many times end up in the oceanyoga pants

I am the first to admit, I love my athletic wear, especially my yoga pants even though I haven’t been to a yoga class in years and am not the most athletic person. On any given day if you were to show up to my house I can say with 99% certainty that I would be sporting a beloved pair of yoga-riffic pants. The study shows that everything from our oceans to the Great Lakes contain high concentrations of these deadly plastic microfibers and that marine life is becoming contaminated as well meaning that when we all eat the seafood we enjoy so much you are basically eating tiny bites of athletic wear, ugh.

University of Florida researcher, Maia McGuire hopes that with more data and studies conducted into the increasing problem of plastics and chemicals invading our water supply that manufacturers of washing machines and water treatment plants will be able to improve water purifying technology to protect marine life.

An article published in early 2017 by Quartz Media found that in 2016 sportswear revenue grew by almost 7% dominating the clothing industry once again. With total global sales for all apparel and footwear reaching $1.67 trillion in 2016 the literal trillion dollar question is, “Will you give up your yoga pants to save our oceans?”.

Ringing in the New Year with PIERS on the Product Side

As many of you know, ChemicalInfo has always provided you with powerful producer information you can trust. Over the last few months, you’ve heard a mouthful about PIERS, The Standard in Trade Intelligence. This Import and Export data integration has provided subscribers with insight to manufacturers’ bulk shipments of chemical products and pharmaceuticals around the world. Well, drum roll please… PIERS just became even more comprehensive, now extending Import and Export data that is searchable by product. So, what does this mean for your business? If you source raw material and pharmaceuticals, import and export data can make you more efficient by helping you:
  • Monitor global trade activity with a complete picture of what commodities are produced, used and sold by regions. This is influential for determining the best price and regions to source from.
  • Make fast and insightful purchasing decisions by providing cost baselines, that are valuable in buying negotiations.
  • Improve differentiation between Manufacturers and Distributors based on Import & Export activity of each supplier.
If you’re in Sales & Marketing then it’s probably your job to find new customers. Well great news; import and export data will help improve your daily activities by:
  • Defining saturated and vacant markets for business growth. This knowledge helps streamline your decision making by verifying company growth initiatives before investments are made.
  • Gaining a competitive advantage by keeping up with your competitors in order to tailor your business decisions.
  • Qualifying your leads by providing insightful information into suppliers’ product pricing and volumes. These purchasing patterns allow you to prioritize leads, in addition to preparing for more powerful price negotiations.
As Ernie Cote, ChemicalInfo Chief Executive Officer, said “The business intelligence tools created by PIERS allows us to identify trends in the chemical industry based on the companies and specific commodities being shipped around the world, and apply that knowledge to our decision making.” As many of you know, ChemicalInfo’s services have always been designed to make you more effective and efficient in your sourcing and selling activities. Now, more than ever, PIERS allows us enhance that knowledge by providing trade activity on top-searched products. About PIERS PIERS is the most comprehensive database of U.S. waterborne trade activity in the world providing information services to thousands of subscribers globally. Launched more than 35 years ago, PIERS was the first venture in digital global trade intelligence and quickly became the industry standard for accuracy, reliability and insight. Our unique infrastructure and proprietary technology allow us to not only publish import data, but also complete coverage of U.S. export transactional data. PIERS is a division of JOC Group Inc., and a sister company of The Journal of Commerce.  For more information about customized solutions from PIERS, visit

Brief on the 2014 American Chemical Society Green Chemistry Institute (ACS GCI) Annual Conference

Learn, Network & Collaborate by Joining ACS GCI Industry Roundtables

The Annual Green Chemistry & Engineering Conference (GC&E) is the oldest and most influential event in the field of green chemistry in the United States. The event took place this year on June 17 – 19 in Bethesda, MD in the Washington DC area and was organized by the American Chemical Society Green Chemistry Institute (ACS GCI). As usual the event reunited hundreds of chemists and engineers from all over the world interested in improving the environmental footprint, health & safety of the chemical industry.

The event featured over 25 technical sessions and importantly industry had a prominent role showcasing industrially relevant technologies.  In fact, the ACS GCI Industry Roundtables organized more than half of the conference this year. These Roundtables are non-competitive, sector-specific collaborations designed to facilitate the integration of green chemistry and engineering throughout the global chemical industry.  With limited budgets and time constraints, yet a plethora of conferences to choose from the industry practitioners in the Roundtables assured content with high implementation potential. The event was also designed to ensure effective networking between academia and industry as well amongst the companies along the value chain starting from hydraulic fracturing oil and gas industry to chemical manufacturers and all the way to business to consumer pharmaceutical and formulator companies. This approach optimized the chance of keeping up to date with the latest thinking in science and technology while facilitating at the same time productive business connections and collaborations.  The Chemical Manufacturer’s, Pharmaceutical and Formulator’s Roundtables met these needs by targeting speakers and discussing impactful alternatives, while simultaneously hosting meetings and networking events throughout the conference.

Technical sessions addressed industrially-relevant greener alternatives

Demonstrating the translation of academic research into industrial application was the focus of a session on commercializing research advances.  Prof. Robert Maleczka, Jr. of Michigan State University presented in series with Dr. Shane Krska of Merck & Co., Inc. and Dr. Jossian Oppenheimer of The Dow Chemical Company to demonstrate the seamless integration of academic research and industrial implementation sides by showing their advances in catalytic C-H borylations.

The event included a stream on bio-based chemicals and their role in the supply chain for various industries. Speakers from Arizona Chemical, Dixie Chemical, Sigma Aldrich (all associated with the Chemical Manufacturer’s Roundtable), as well as NatureWorks LLC, LanzaTech, Corbion, and others shared their latest technologies and products with an audience eager to learn more about this rapidly growing industry.

Closer to the Formulator’s Roundtable activities, J&J Consumer Products, Seventh Generation, State Industrial Products, Rochester Midland Corporation, DuPont, the American Cleaning Institute, Trucost, and the US Federal Trade Commission addressed the design of greener consumer products with comparable performance and price.

For the second year in a row, the event included a session on sustainability aspects of hydraulic fracturing. Companies like Halliburton, Solvay, Akzo Nobel, and Trican Well Service shared their experiences, including, but not limited to, safer alternatives to biocides and crosslinked gel systems.

Targeted networking; the right connection is priceless

The 4th Annual ACS GCI Roundtable Poster Reception held on the evening of June 18 was designed to foster networking across the value chain to develop innovative, more sustainable products & processes.  Sponsored by Flotek Industries, LAUNCH, and ILSI Health and Environmental Sciences Institute, industry mingled with key government agencies and other organizations.  Importantly, over 85% of survey respondents indicated they learned about a greener technology, material, market need, or research idea that may be applicable to their organization.  For example, Dr. Philip G. Sliva of Amway reported he “had just read about a new solvent in C&EN recently and the Roundtable Poster Reception had the very material showcased. I was able to get samples and literature arranged then and there.”

Effective Collaboration: Leveraging resources of others to maximize return on investment

The ACS GCI Roundtables are designed to leverage the resources of peer companies working together non-competitively to address common challenges related to the implementation green chemistry and engineering.  By working collaboratively, the Roundtable has more influence than any one company could have alone.

Hosting meetings in concert with the conference, the Roundtables not only make good use of their members’ time but are able to simultaneously meet with influential organizations in the Washington, DC area.  Interestingly enough meeting in person is not critical as all Roundtable meetings are web-based to allow for global participation. For example some organizations such as Pennakem LLC, a biobased product manufacturer, and Novartis , a pharmaceutical company headquartered in Basel, Switzerland, participated via web.

The ACS GCI Chemical Manufacturer’s Roundtable addressed ongoing projects and discussed opportunities with guests from the US Department of Agriculture on developments in the BioPreferred Program, as well as guests from the Department of Commerce, US Department of State, and others.

The ACS GCI Pharmaceutical Roundtable, now in its ninth year, focused on advancing projects on tool development, research grants, metrics, as well as explored a potential international collaboration on education.

The focus of the ACS GCI Formulators’ Roundtable was meeting with the US Environmental Protection Agency Design for Environment Program and International Fragrance Association (IFRA) North America to address challenges in developing products to meet the fragrance standard.

At last, but not at least, the ACS GCI Hydraulic Fracturing Roundtable announced it is now open for membership and began developing goals for 2014-2015.

Looking ahead to 2015, the bar will be raised as the ACS GCI Roundtables celebrate a significant milestone; the ACS GCI Pharmaceutical Roundtable will celebrate its 10 year anniversary.  Plans are already underway to further optimize industrial impact for the 19th Annual Green Chemistry & Engineering Conference in July 14- 16, 2015.

Julie B. Manley, Guiding Green LLC, 457 E. Mier Road, Sanford, MI, USA 48657; Tel: 815-325-4974;

Stop paying lip-service to your internal customers: Five things Procurement organizations should start doing now to meet and exceed internal customer requirements

“Procurement needs to be more proactive versus the Business initiating projects”

“Procurement needs to be an integral part of the team”

“Consult the Business before implementing any process improvement”

“Procurement needs to issue the POs in a timely manner. Waiting 3 days on a PO is unacceptable”

These are some comments we’ve recently heard when conducting a Stakeholder Survey (Voice of the Customer) as part of a broader Procurement benchmark for different clients. We often hear that Procurement is focused on meeting and exceeding customer requirements, but benchmarks from Hackett’s Procurement database shows otherwise. The chart below shares that 30% of Non-World-Class (Non-WC) organizations rated Procurement as an Administrator while only 15% of Non-WC organizations rated Procurement as a Valued Business Partner. So, if this is the stakeholder’s perception of the Procurement organization, what are some things you can do quickly to change this perception?

Other than changes to the organization structure, there are five things that we believe Procurement can quickly do to improve internal customer perception and exceed internal customer requirements:

  1. All Procurement resources should be customer focused and empowered
  2. Dedicate specific Procurement resources to Help Desk activities
  3. Start conducting monthly training to educate internal customers
  4. Create a monthly/quarterly newsletter and share recent projects, success stories and upcoming projects
  5. Create an internal website to share Procurement information: FAQs, contact information, approved suppliers, success stories, process documents, etc.

All Procurement resources should be customer focused and empowered. We often hear the comment that perception is reality – unfortunately, there is some truth in this. As Procurement resources are typically focused on assisting end-users with different processes in Procurement, all Procurement individuals (whether they are internal client-facing or not) should be customer focused which means being helpful in problem solving and troubleshooting, being proactive, being a good listener, and feeling empowered to fix processes that are broken. The term ‘fit-for-purpose’ or ‘fit-for-risk’ comes to mind when addressing broken processes. As Procurement works to address issues identified by its internal customers, it should determine whether the process is adequate or overkill for what the internal customer is trying to accomplish based on the value and appropriate risk appetite of the organization.

Dedicate specific Procurement resources to Help Desk activities. Procurement activities are a complex string of processes. As such, we should expect our internal customers to have plenty of questions related to the process, status of transactions, etc. Dedicating specific Procurement resources to answer questions from internal customers is one of many ways Procurement can help address and resolve questions in a timely fashion. However, it is important to note that the more knowledge the Help Desk resources have about the usage of Procurement technology, status of sourcing events, process for sourcing, and a broad understanding of Procurement, the better they will be at being able to provide first-contact resolution.

Start conducting monthly training to educate internal customers. Conducting monthly/ongoing training to internal customers will help provide them with the knowledge and latest information to perform their jobs. Ultimately, this will also help Procurement. There are various types of training that can be provided to include:

  • How to create transactions
  • How to create spend analysis reports
  • How to identify approved suppliers
  • How to use e-catalogs
  • How to maneuver the ERP maze

During these sessions, it would also be helpful to document the various issues that each of the internal customers faces. By addressing these issues, Procurement will be able to 1) ensure that internal customer requirements are met and 2) improve internal processes.

Create a monthly/quarterly newsletter and share recent projects, success stories and upcoming projects. Most of Procurement’s work goes behind the scenes and rarely do we share our success stories for one reason or another. However, creating a monthly/quarterly newsletter will help provide our Internal Customers with additional information on how the Procurement organization is able to assist, help identify new projects and bring to light creative ideas from previous projects. In addition, it is also a way of demonstrating value that Procurement organizations bring along with some shameless self-promotion.

Create an internal website. While the monthly newsletter is focused on sharing the latest news, an internal website is another way of allowing our Internal Customers to perform self-service. There are various reasons to create an internal website including:

  • Sharing of information with our internal customers
  • Providing them a portal to log issues
  • Providing them ability to self-diagnose and resolve issues

As a member of the Procurement organization, our role is to help support internal customers by listening, understanding, meeting and exceeding their expectations. Being front and center to our internal customers is important. Hopefully, these 5 activities can quickly help your Procurement organization change your internal customers’ perception.

As Outsourcing Relationships Evolve, Vaccine Production Will Continue to Shift to CMOs

The vaccine contract manufacturing market currently accounts for less than 1 percent of the total vaccine market — approximately $705M of $33.7B — but it is expected to grow over the next decade.  Varying factors will influence the growth of the contract manufacturing market segment, including overall growth of the vaccine market, especially in emerging markets, as well as the shift in the dynamic of outsourcing relationships.  Traditionally, vaccines had been viewed as a low-margin business with high barriers to entry.  Complexity of development and production, combined with significant fixed costs, low profit margins, and overregulation had limited competition among vaccine manufacturers and supposedly restricted innovation. However, advances in both preventative and therapeutic vaccines have renewed interest and brought about competition in this market segment. Among Nice Insight survey respondents, the primary area of therapeutic focus for vaccine production outsourcers is infectious diseases, at 71 percent. Increased global demand for the influenza vaccine has contributed significantly to the growth of the outsourced vaccine market — especially since the vaccine doesn’t offer long-term immunity and must be administered annually. Support and media exposure from organizations such as the International AIDS Vaccine Initiative help to keep the important role of vaccines in healthcare in the forefront and drive attention toward developing vaccines for diseases that currently have no cure. This exposure, coupled with recent reports of progress in two separate approaches to provoking an immune response to HIV, certainly contribute to the increasing number of biopharmaceutical companies interested in developing or manufacturing vaccines. Oncology is another key area for vaccine advances, with 52 percent of vaccine outsourcers engaged in this therapeutic category.  Nationwide immunization programs for HPV (human papillomavirus) vaccination established in 2008 in the U.S. and Europe have strengthened this market to an estimated value of $2.2B by 2018. The efficacy of the vaccine, as well as the expansion of the target audience to include both males and females, has secured the HPV vaccine’s future and made it a strong candidate for outsourced production. Anticipated shifts in vaccine production from innovators to contract manufacturers influenced the decision to add this service to the Nice Insight Biopharmaceutical Outsourcing Survey for 2014.  At present, the data show 13 percent of all respondents will outsource vaccine production, or 40 percent of respondents who outsource biomanufacturing. Big Pharma and Big Biotech account for the majority of vaccine outsourcing, comprising 59 percent of the buying market.  Emerging biotech and emerging pharma each comprise approximately 15 percent of the buying market, and specialty pharma accounts for the remaining 10 percent. Selecting An Outsourcing Partner For Vaccine Production While quality and reliability consistently hold the top two positions among partner attributes, when it comes to selecting an outsourcing partner for vaccine production, the importance of productivity and innovation move upwards, causing a company’s regulatory track record to shift to sixth position. In fact, when reviewing the companies most likely to be considered for an outsourced vaccine project, the top five companies scored best in quality, reliability, and productivity.  This ranking makes sense, as reliability is directly linked to security in supply, and productivity is directly linked to time-to-market. Security in supply is particularly important for routine vaccines, whether they are childhood immunizations or, like the newer HPV vaccine, administered during adolescence.  Time-to-market becomes a considerable issue when there is a surge in the need for a vaccine, such as the flu vaccine when a particularly bad strain hits or during times like the swine flu and bird flu outbreaks. As CMOs continue to be viewed as trusted partners in bringing drugs to market, their expansion into segments such as vaccine production will continue to add value to drug innovators in terms of product security, improved time-to-market, and increased capacity — all traits where the positive impact is passed on to the health of the consumer. By Kate Hammeke, Director of Marketing Intelligence at That’s Nice cSurvey Methodology: The Nice Insight Pharmaceutical and Biotechnology Survey is deployed to outsourcing-facing pharmaceutical and biotechnology executives on an annual basis. The 2013-2014 report includes responses from 2,337 participants. The survey is comprised of 240+ questions and randomly presents ~35 questions to each respondent in order to collect baseline information with respect to customer awareness and customer perceptions of the top 100+ CMOs and top 50+ CROs servicing the drug development cycle. Five levels of awareness from “I’ve never heard of them” to “I’ve worked with them” factor into the overall customer awareness score.  The customer perception score is based on six drivers in outsourcing: Quality, Innovation, Regulatory Track Record, Affordability, Productivity and Reliability. In addition to measuring customer awareness and perception information on specific companies, the survey collects data on general outsourcing practices and preferences as well as barriers to strategic partnerships among buyers of outsourced services.